glutathione s transferase ncbi The Multifaceted Role of S-Transferases in Health and Disease Simplified scheme of action of

Overexpression of thioredoxin reductase 1 can reduce DNA damage, mitochondrial autophagy and endoplasmic reticulum stress in Parkinsons disease

By designing a thiol-activatable fluorescent gold nanoprobe that can bind to serum protein and be transported to the liver, we non-invasively imaged the biotransformation kinetics in vivo at high specificity and examined this process at the chemical level

Increased expression of insulin-like growth factor I is associated with Ara-C resistance in leukaemia

The results of the immunofluorescence staining in the gastrocnemius muscle at 8 weeks showed that ROS accumulation and release increased after SCI, the ROS-positive cell rate increased significantly, the percentage of ROS-positive area also increased, and the immunofluorescence intensity was significantly enhanced

Mitochondrial DNAs unique heteroplasmy feature where mutated genes coexist with healthy genes enables a technique that degrades mutated genes using enzymes like polymerase gamma whilst allowing healthy mtDNA to multiply and restore normal copy numbers

Then human IgG concentration normalized plasma samples were added and incubated for 1 h at RT