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Avoid alkaline pH conditions and prolonged exposure to elevated temperatures that promote peptide degradation

Nanoparticles from small- and large-scale batches were indistinguishable in core size and spectral properties, as verified by TEM and UV/Vis (Fig

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a MHC complex comprising one or more entities (a-b-P) n , wherein a and b together form a functional MHC protein capable of binding a antigenic peptide P, and wherein (a-b-P) is the MHC-peptide complex formed when the antigenic peptide P binds to the functional MHC protein, said MHC complex optionally further comprising a multimerization domain comprising a carrier molecule and/or a scaffold