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We discuss the cellular and molecular mechanisms of agingand how specific behaviors, such as fasting, regular exercise and NAD-boosting compounds like NMN, can activate the body's natural longevity pathways

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Others, such as corynoxine, target upstream phosphatases such as protein phosphatase 2A to dually inhibit AKT signaling (98), whereas Gboxin and its analog Y9 trigger lysosomal dysfunction and autophagic impairment (99)

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Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of tuberous sclerosis complex