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In addition to the immunomodulatory properties of polyphenol compounds, they also showed effective antioxidant properties

The transcriptomic analysis indicated that the upregulation of Gsto2 in iSPNs affected redox homeostasis and created a hyperdopaminergic state similar to pre-symptomatic Huntingtons disease

However, SSRIs have decades of human evidence showing efficacy in millions of patients, while BPC-157 has zero human trials for depression

Stockley, R

thereby, the CREB1-NRF2 signaling pathway potentiates the function of MSCs, which was shown to increase their therapeutic potential in a humanized mouse model of graft-versus-host disease [37]