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Lipotoxicity in HepG2 cells triggered by free fatty acids

Utilizing retinal melanin as an endogenous detection material and intravenously injected gold nanorods as exogenous detection material, PT-OCT observes the photothermal effects on endogenous and exogenous substances in the retina, effectively adding a new source of contrast for structural OCT and marking a new era in ocular OCT examinations

Batchuluun, B., Pinkosky, S

Furthermore, mitochondrial membrane potential (m) decline, increased mitochondrial outer membrane permeability and mitochondrial DNA (mtDNA) damage have been identified as key regulatory factors in ferroptosis (10,11)

Therefore, patients should consult with our healthcare providers to thoroughly discuss the potential benefits and limitations of this therapy in conjunction with their current treatment plans

Its application resulted in increased cell proliferation, a significant rise in alkaline phosphatase (ALP) activity, positive Alizarin Red S staining, and the formation of mineralized nodules, as confirmed by EDX-SEM analysis