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We believe that by capitalizing on various critical contributions to the understanding of the AR structure and function and advancements in crystallography techniques, the future of rational drug design for better antiandrogens for the treatment of prostate cancer remains bright

The mild elevation of -BB, coupled with a conserved amino acid change, suggests that D72G is a hypomorphic, milder variant resulting in a quantifiable metabolic phenotype where small deviations in -BB levels are metabolically tolerable in C

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doi: 10.1089/thy.2000.10.1043 19 NordioM

204,205 Although many HD patients may have plasma ascorbic acid levels less than the normal range, 206,207 whether this reflects a clinically significant deficiency is uncertain

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