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*Correspondence: Daniel Hargbl Madsen, [email protected] This article was submitted to T Cell Biology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Potential Benefits (Reported in Literature) May support cellular energy production and mitochondrial function through replenishment of NAD+ pools [1] [8]

For plant-based diets, include B12-fortified foods or supplements

Pulsed Dose: ET exhibits non-linear pharmacokinetics, high systemic accumulation, active renal reabsorption, and an exceptionally long human half-life of approximately 30 days

2.5 (compound D at 0.03 mM and 0.1 mM)