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Among aminopenicillins, AMP was chosen since it shares the nuclear bicycle structure of AX and the presence of amino functionality in its side chain

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Acknowledgments The authors thank Akiko Yamashita, Chihiro Ishizaki, Yoriko Setsuda, and Maki Ozone at Kyoto University Hospital Department of Nephrology for their excellent technical assistance

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Maleimides are another group of reagents employed for the selective coupling of a ligand through sulfhydryl groups

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