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An increase in spontaneous abortions was documented in spouses of agricultural male workers who were in direct contact with pesticide chemicals including DDT on a daily basis [352]

Furthermore, cellular damage in ALI/ARDS occurs mainly through caspase-dependent pathways, causing cellular pyroptosis

Again, its main effect on cells of the monocyte/macrophages lineage is anti-inflammatory and pro-tolerogenic activity: first of all, in vitro studies on human monocytes or total PBMCs (peripheral blood mononuclear cells) evidenced a reduction in the production of proinflammatory cytokines (i.e

Studies using a recombinant HSV-1 expressing IL-2 reported the presence of auto-reactive T cells in the brain and CNS demyelination, supporting the hypothesis that both, virus and IL-2 play roles in the demyelination process and that HSV-1 could be important at initiating the destruction of myelin in the presence of elevated levels of IL-2 (Osorio et al., 2005

By simulating biological processes at several phasestarget identification, SMN, payload design, biodistribution, and simulation of extracellular and intracellular interactionsAI helps to design and optimize SMNs

Subsequent treatment of Cd-exposed CRC cells with varying concentrations of RSV resulted in a reversal of the Cd-induced migratory and invasive phenotype