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To optimize the chemical properties of erastin, Yang et al

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This water-soluble vitamin is necessary for brain and central nervous system function, blood cell formation, and the metabolism of every cell in your body

In EcGGT, replacement of the second and third residue, respectively, with alanine (T392A) and glycine (H393G) impaired autoprocessing, suggesting that the small subunit N-terminus is more crucial than the large subunit C-terminus during autoprocessing (Hashimoto et al., 1995)

Khosrowbeygi et al

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