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The rise and fall reflect the action trend of drugs, and the toxicity reflects the safety degree of drugs

BBB primary isolated bovine brain capillary endothelial cells a ligand that is endocytosed and/or transcytosed into and/or through the target cell is herein defined as a ligand that is endocytosed or transcytosed into or through a BCEC or MDCK target cell at a rate that is at least 5, 10, 20 or 50% enhanced as compared to control conditions selected from a) cells lacking expression of GSH transporters

Sah AK, Suresh PK, Verma VK

Keeping in mind both the explicit purpose of international targets to guide progress, their implicit motivations, and the limitations identified with the current target structure, we propose an alternative methodology for setting international development targets that remain ambitious but are more likely to be achievable

Drug Use 5, 155