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GSH is an important component of the cellular antioxidant system and plays an important role in the treatment of tumours, and GSH can also trigger ferroptosis by interfering with cystine/glutamate reverse transporter proteins (systems Xc - ), inactivating GPX4, or depletion of GSH [7]

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in 1996, which showed that high dose of intratracheal Mtb challenge led to progressive fatal infection in Philippine cynomolgus monkey (Walsh et al., 1996)

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The livers contribution to blood acylcarnitine levels is also closely related to the risk of cardiovascular events

This reduction subsequently disrupts the cellular energy balance and exacerbates cellular stress under conditions of oxidative stress