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CAR has multiple phosphorylation sites in its ligand-binding and DNA-binding domains, with Thr38, a site phosphorylated by PKC, mainly implicated in regulating its nuclear translocation, while Ser202 also plays a role (78)

34 There is mounting evidence that mitochondrial dysfunction may be present in a significant subset of children with autism and contribute to the multisystem abnormalities seen in some autistic children

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Most studies demonstrating the antihypertensive properties of kefir have been performed in animal models, with limited human clinical validation