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However, the addition of iodomethylcholine, a gut microbial choline TMA-lyase mechanism-based inhibitor, significantly reduced the plasma level of TMAO, ameliorated renal function and inhibited renal tubulointerstitial fibrosis in isoproterenol-induced CKD rats

10.1007/s10545-016-9972-7 J

Suppression of Oxidative Stress by -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

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Flow data was acquired using FlowPilot software (Union Biometrica), and subsequent data analysis and normalization are detailed in the Statistical Analysis methods section

We confirm that this study was carried out in compliance with the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines and all methods were performed following the relevant guidelines and regulations