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Notably, we discovered that the immune checkpoint B7h4 was upregulated in a large fraction of iCCAs, where it was expressed on the tumor cell membrane and intracellularly

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Methods Subjects and pancreatic sections Paraffin-embedded pancreatic sections (5 m) from formalin-fixed biopsy specimens surgically excised from the pancreatic tail region of 4 living individuals with newly diagnosed type 1 diabetes from DiViD, 22 formalin-fixed cadaveric pancreases also from the pancreatic tail supplied by nPOD and 1 pancreas at post-mortem from EADB, UK, were analyzed (Krogvold et al