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LC-MS/MS Quantitation For the LC-HRMS method, acetyl-CoA and other short-chain acyl-CoAs were analyzed as previously described (Frey et al ., 2016) using an Ultimate 3000 quaternary ultra-high performance liquid chromatograph coupled to a Q Exactive Plus mass spectrometer (Thermo Scientific), with modifications for a two-column setup

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501 Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the dysfunction of upper and lower motor neurons

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A CALL TO ACTION A large-scale, long-term study of both prenatal and postnatal effects of acetaminophen exposure on the incidence of autism, attention deficit with hyperactivity, and asthma should be conducted

In molecular docking, all targets except NFKB were validated by redocking with their native ligands