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Tumor-derived exosomal circRNA_102481 contributes to EGFR-TKIs resistance via the miR-30a-5p/ROR1 axis in non-small cell lung cancer

Wu Y, Kong L

Cytotoxicity assays, including MTT and SRB, showed significantly reduced toxicity for the PEGylated nanoparticle formulation compared to free tolcapone (cell viability exceeded 85% at 10, 25, and 50 M of the formula after 24 and 48 h of treatment)

Peucedanum ostruthium shows anti-tubercular potential in silico, with nine bioactive compounds mapped to 256 TB-related genes

People who have a genetic predisposition for lower GSH production have an even greater challenge maintaining sufficient GSH

In vivo studies showed that specific deletion of myeloid cell Gpx4 in mice exhibited SLE-like clinical manifestations, which could be alleviated by treatment with liproxstatin-1, an ferroptosis inhibitor, and attenuated disease progression