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Brain Res 1071:5462

Muscle Repair

Tail vein blood (~5-10 l) was collected serially at 0, 30, 60, 90 and 120 min post-challenge through the tail-nick method (19) The blood collection procedure was approved by the Institutional Animal Care and Use Committee of City of Hope in accordance with the NIH Guidelines for Survival Blood Collection in Mice and Rats ( Blood glucose concentration was measured with an Accu-Chek Compact Plus glucometer (Roche Diagnostics Ltd.)

A nearly 25% average weight reduction in less than a year is unprecedented in the published literature

Use of guidelines improves the neurological outcome in glutaric aciduria type I

Kyle, PhD