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FIGURE 3 The first choline-TMA lyase inhibitor, DMB, was identified by Wang and colleagues, which is shown to non-lethally inhibit distinct microbial TMA lyases, and reduce TMAO levels in mice fed a high-choline or L-carnitine diet (Wang et al., 2015)

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20.12 A nevus spilus is characterized by a large tan patch with superimposed small dark macules 20.9.2 Histology Most authors consider nevus spilus to be synonymous with speckled lentiginous nevus, and thus the histologic changes will be described as if they refer to the same entity [66, 67]

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