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As observed previously 13 , the putative flavan-3,3,4-triol ( 4 ) was not stable during purification, and confirmatory time-course experiments showed almost complete degradation of the intermediate ( 4 ) within 24 h (Extended Data Fig

Neuroscience 145:12331248 Twisk FN, Maes M (2009) A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS): CBT/GET is not only ineffective and not evidence-based, but also potentially harmful for many patients with ME/CFS

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In practical applications, individualized adjustments should be made based on animal weight, physiological status, and severity of the disease