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They also work in different ways

Oxidant stress and acetaminophen hepatotoxicity: mechanism-Based drug development

FANCD2 influences replication fork processes and genome stability in response to clustered DSBs

Furthermore, iron accumulation is even higher in the substantia nigra in Parkinsons disease (PD) and in anatomical regions affected by -amyloid plaques and tau protein loading in Alzheimers disease (AD) suggesting iron overload as a key factor in the pathogenesis of common neurodegenerative diseases [80, 81]

Small molecules such as Alda-1 could serve as therapeutics by restoring the naturally efficient regulatory mechanisms of 4-HNE that are debilitated in disease conditions

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