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Each temperature excursion reduces that window proportionally: a vial exposed to room temperature for 6 hours loses approximately 34 days of viable shelf life

Because the amount of marker present in the body is known (i.e., the difference between the amount originally injected and the amount excreted in urine) and the concentration is measured, the volume of distribution of the marker substance can be calculated as follows: where SAMPLE PROBLEM

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Theyre looking into a variety of factors that may be involved, though they arent sure how yet