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Necroptosis drives motor neuron death in models of both sporadic and familial ALS

CDO in both liver and adipose tissues responds to changes in dietary intakes of protein and/or sulfur amino acids over a range that encompasses the requirement level, suggesting that cysteine homeostasis is very important to the living organism

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As a major hydroxy peroxide scavenger, GPX4 can suppress ferroptosis thus playing an essential role in HSCs homeostasis

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