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doi: 10.3389/fmed.2025.1535673 Received 27 November 2024 Accepted 25 March 2025 Published 04 April 2025 Volume 12 - 2025 Edited by Vasilios Kotsis, Aristotle University of Thessaloniki, Greece Reviewed by Panagiota Anyfanti, Aristotle University of Thessaloniki, Greece Raina D Ramnath, University of Bristol, United Kingdom Updates Copyright 2025 Wang, Zhang, Qu and Zhou

Table 1 Summary of the results from the Exploratory Factor Analysis (EFA) on the SDS 33 items obtained from Sample 1 ( n = 501)

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A comparison was performed between the predicted exposure using in silico methods (described in item 2.3) and the measured bioactivity responses (i.e., PoDs as determined using the state-space model approach)

Nonetheless, its broad-spectrum antibacterial activity can make it an important treatment option when other antibiotics fail or cannot be used