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In recent years, ferroptosis, a form of regulated cell death dependent on iron and lipid peroxidation, has been demonstrated to play a key role in intestinal oxidative stress during IBD

Vitamin B 3 (niacin) also seems to be a promising compound for safely enhancing myelin phagocytosis by microglia (Rawji et al., 2020)

Guevara et al., 2025)

All manuscripts analyses were based on the genetic sex inferred from sequencing data, cross-referenced with the reported sex in the clinical records

2-Methoxyestradiol exhibits potent apoptotic activity against rapidly growing tumor cells and possesses antiangiogenic action

[DOI] [PMC free article] [PubMed] [Google Scholar] [149].Maes M, McGill MR, da Silva TC, Abels C, Lebofsky M, Maria Monteiro de Araujo C, Tiburcio T, Veloso Alves Pereira I, Willebrords J, Crespo Yanguas S, Farhood A, Beschin A, Van Ginderachter JA, Zaidan Dagli ML, Jaeschke H, Cogliati B, Vinken M