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Among the most common chronic diseases, heart disease, cancer, obesity, and type 2 diabetes (T2D) constitute the leading causes of disability and death in the United States

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Additionally, dosing at 20 mg/kg body weight or greater resulted in mild to severe fundic lesions on ophthalmologic examination (change in color of the fundus, central or generalized retinal degeneration), abnormal electroretinograms (including blindness), and diffuse light microscopic changes in the retina

S -transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-( S -glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene"

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