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The cannabinoid-mediated reduction in neurotransmitter release is achieved by the reduced influx of presynaptic Ca 2+ due to the inhibition of voltage gated Ca 2+ channels and of adenylyl cyclase, which downregulates cyclic adenosine monophosphate and protein kinase A, two cellular constituents involved in increasing the influx of Ca 2+ (Castillo et al., 2012)

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Here, we report a reversible reaction-based fluorescent probedesignated as RealThiol (RT)that can quantitatively monitor the real-time glutathione dynamics in living cells

doi: 10.1111/bjd.20596