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FIGURE 4 7 Ferroptosis-based treatment strategies for MM 7.1 Active ingredients of natural products The partial inhibition of cell death by Ferrostatin-1, Liproxstatin-1, or Deferoxamine, alongside evidence that natural product extracts induce MM cell death, implicates ferroptosis in MM cell demise

Nat Rev Clin Oncol (2017) 14:20320

239 The body increases thermogenesis, primarily through non-shivering thermogenesis in brown adipose tissue, which involves increased FAO and uncoupling of OXPHOS to generate heat rather than ATP

Why use citrulline malate, which yields a lower dose of citrulline

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Future studies on how PPs might interact with nCDs-associated molecular receptors and signaling pathways (in particular inflammation) and their exact mode of action in relieving AFs end effects should be conducted to confirm their efficacy and safety for medical management of mycotoxins