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(34i) MicroRNA-142-5p may contribute to Hashimoto's thyroiditis by targeting CLDN1.(34j) INCIDENCE AND DISTRIBUTION The incidence of Hashimoto's thyroiditis seen in practice is unknown but is roughly equal to that of Graves' disease (on the order of 0.3 - 1.5 cases per 1,000 population per year.)(35-37) The disease is 15 - 20 times as frequent in women as in men

Patients may report changes in exercise recovery, energy, focus, or daily performance when therapy is appropriate and well tolerated

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10.1038/ncb1524 108 SiebelC.LendahlU