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Surgical ischemia, trauma, and circulatory perturbations can derail mitochondrial function in immune cells, leading to excessive DAMPs release, inflammasome activation, metabolic failure, and ultimately tissue damage and immunosuppression

Quantitative detection was performed using an UHPLC-ESI-QQQ-MS (Agilent 1290 and 6460 triple quadrupole mass spectrometry series)

Following a single intravenous administration, approximately 76% of the levocarnitine dose was excreted in the urine during the 0 to 24 hour interval

B-group vitamins are water-soluble, the excessive amount is generally excreted out of the body through urine

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