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An active RISC complex targets mRNA for degradation and inhibits gene expression, facilitating PTGS [99]

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Paradoxically, the ROS-limiting capabilities of p53 have also been implicated in facilitating tumor growth by suppressing excessive oxidative stress, which could cause cancer cell death (Humpton And Vousden 2016)

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Shen JL, Man KM, Huang PH, Chen WC, Chen DC, et al