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Other symptoms include: Sensitivity to hot and cold Pain that wakes you up at night Pain in your jaw, ear or neck Pain that gets worse when you lie down Pain when chewing or biting Redness Swelling Discolored or loose teeth Bad breath or taste Swollen lymph nodes in your neck or under your jaw Fever In severe cases, swelling may affect your vision or breathing

5 Safety profile In vitro and in vivo studies on the toxicity of caudatin have shown that it exhibits a relatively low toxicity profile in terms of its therapeutic efficacy (Figure 6)

DeVault KR, Castell DO

Poli, G., Albano, E

Pain behavior was quantified periodically at 5- and 35- min intervals (representative values of phases 1 and 2) by counting the number of flinches exhibited by the injected paw after injection

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