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10.1186/s13024-016-0084-5 Mol

Prokineticin receptor inhibition with PC1 protects mouse primary sensory neurons from neurotoxic effects of chemotherapeutic drugs in vitro

132 The formation of aggregated mutant HTT proteins in neurons leads to reduced energy production, oxidative stress, and neurodegeneration

The processed protein structure was then saved in.pdbqt format

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This underscores the need for future studies employing organ-specific interventions, such as topical delivery or tissue-targeted knockouts, to disentangle systemic versus skin-specific contributions