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Microbial composition in the human GI tract and capability for digesting the dietary fiber Microorganisms in the intestine of humans fluctuate from a few hundred to 100 trillion, such as 10 3 cells/g in the stomach, ~ 10 7 cells/g in the small intestine with a more significant part of facultative anaerobes, and ~ 10 13 cells/g in the colon which obligate anaerobes make up the majority fraction (54, 55)

High doses of vitamin B12 can lower potassium levels, which may stress cardiac function

Appropriate medical supervision is necessary when using this medication

Mercury and other heavy metal contamination can be a concern with fish-derived supplements

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells