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2 The mechanism of ferroptosis and iron homeostasis The critical molecular mechanism of ferroptosis involves regulating the balance between oxidative damage and antioxidant defense ( Intracellular iron accumulation is a key factor in ferroptosis, attributed to several fundamental processes of cellular metabolism

Moreover, early studies on HIV-1-infected subjects associated GSH deficiency with a poor lymphocytic response and impaired survival following HIV-1 infections 28,29,30 , implying a role for GSH in disease

The differences in microbiota composition were not statistically significant in the post-LT group when compared to healthy controls, suggesting that LT restores, at least partially, the microbiota composition

DOI: 10.1007/978-1-4020-8830-8_12 42

coli protein, which depends on oxidation by DsbA for its activity, in different mutants

To date, not even a single drug is available, even after neuroprotective tests, which could delay or stop the progression of the disease