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Description

Subjects homozygous for low TPMT activity have a high risk of myelosuppression after treatment with standard dose of azathioprine

Reduced expression of E-cadherin can loosen cell adhesion, facilitate cell movement, and accelerate cell metastasis and invasion

Oxidative stress in Cancer

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We validated radioprotection using WR-1065, the active form of Amifostine and tested other reported radioprotective drugs including Edaravone, Tempol, N-acetylcysteine, Rapamycin, Ex-Rad, and Palifermin