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The preliminary workup consisted of a full blood count and haematinics (to rule out haematinic deficiency-related oral ulceration), connective tissue disease screen, renal and liver profiles, HbA1c and syphilis serology

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26,27 However, even when these combustion by-products are removed, as in nicotine-only products, CV toxicity largely persists, because nicotine itself is harmful, 8,9 E-cigarettes: less harmful, not harmless E-cigarettes have often been marketed as harm reduction tools