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In cases thus located or in the case of hilum adenopathies and subsequent stenosis of biliary ducts, magnetic resonance cholangiopancreatography may reveal the stenosis with dilatation of intrahepatic bile ducts, similar to that in a Klatskin tumor [52]

G., Steiner, J., Guest, P

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4, 5 Among the growth factors involved in the proliferation step, hepatocyte growth factor (HGF), transforming growth factor alpha (TGF ) and epidermal growth factor (EGF) induce hepatocytes to override the mitogen restriction point located at 2/3 of G1 phase

FIGURE 3 4.2.2 ABC transporter mediated drug efflux ABC transporters utilize ATP hydrolysis to efflux gemcitabine and its metabolites from cells, thereby reducing intracellular drug concentrations and contributing to resistance

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