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cannot be used in compounding unless the FDA authorizes their use through rulemaking

doi: 10.1007/s12013-013-9574-z 62 EckertMACosciaFChryplewiczAChangJWHernandezKMPanSet al

ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Brotman et al., 2025)

Archived from the original on November 26, 2017

This creates demand for more targeted approaches that control excessive inflammation while preserving the beneficial aspects of the inflammatory response

doi: 10.1016/j.celrep.2014.06.007