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However, if one component of the redox buffer partitions selectively into the MLO, that would lead to a very different redox environment in the MLO compared to its environment

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Food Policy 2016, 59 , 152164

This context dependence also suggests that, when applying BCAA-related targets for disease intervention, it is necessary to distinguish between two different levels of regulatory modes: the mTOR-driven pro-inflammatory effects caused by enhanced BCAA uptake/transport, and the support provided by changes in BCAA catabolic flux to mitochondrial metabolism and reparative programs, so as to avoid conflating results obtained from different experimental systems

Geffner, D