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doi: 10.1016/j.freeradbiomed.2017.01.009 135

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CD14 high CD16 Monocytes From COVID-19 Patients Exhibit Prominent Oxidative Stress Activity Oxidative stress has been suggested to be a critical host factor in driving immune response exacerbation in several infectious diseases ( Figures 4AF )

Cellular entry of SARS-CoV-2 is mediated by the binding of the viral spike (S) protein to its cellular receptor, angiotensin-converting enzyme 2 (ACE2) 4,5