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The post-treatment follow-up was performed after 12 and 24 weeks of treatment, plus a few days if necessary, so that patients were again evaluated on day 36 of the menstrual cycle (the first occurring after the 12 or 24 weeks of treatment)

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Arginine is also at the center of the different functions associated with M1 and M2 macrophages, being called a small amino acid for macrophage metabolism, a giant controller for mammalian pathophysiology [8]