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But serious health problems can arise for some individuals taking vitamin B12 at higher dosages

& Harold, G

Discussion As one of the most complex biological processes that occur during human life, the wound repair process involves four steps that include inflammation around the site of injury, angiogenesis and the development of granulation tissue, repair of the connective tissue and epithelium, and ultimately remodeling that leads to a healed wound.1 The clinical treatment of skin loss due to severe and massive burns or wounds continues to be a major problem in surgical procedures

Patients who have pernicious anemia, in which intrinsic factor is lacking, absorb little if any of the oral dose of B12, resulting in little or no radioactive material being excreted in the urine

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The non-treated group was used as a control, and cell-penetrating peptide (CPP)-conjugated GHK was used as a positive control