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Updated March 7, 2018

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73 Notably, VSMC-specific EP4 knockout increases vascular inflammation and leads to vascular remodeling and elevated blood pressure

This high rate of RCD may serve a few biological functions including brain tissue morphogenesis, synaptic connection optimization, cell number regulation, and elimination of developmentally obsolete structures (130, 131)

Some limitations with this study include the use of only male rats and lack of assessment of the number and morphology of mitochondria in the brain (Reference Sindhu, Binitha, Nair, Maliakel, Ramadasan and Krishnakumar66)

A much broader range of behaviours were brought under the umbrella of the term autism, said Prof Gina Rippon, emeritus professor of cognitive neuroimaging at Aston University