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Nrf2 is also directly involved in maintaining mitochondrial membrane potential

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Muscle atrophy due to nerve damage is accompanied by elevated myofibrillar protein synthesis rates

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We validated that the FTD3 neurons in our model exhibited reduced glucose metabolism as demonstrated by down-regulated expression of glycolytic enzymes, as well as diminished 13 C-enrichment in lactate produced after metabolism of [U- 13 C] glucose and decreased lactate release

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