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To detect whether overexpression of MUC-1 can regulate ferroptosis-related genes, SLC7A11 and GPX4 expression were detected by qRT-PCR, and the results showed that SLC7A11 and GPX4 were upregulated (Figure 7J)

These results were consistent with Ki-67 staining, HE staining and TUNEL assay, which showed that treatment with the NAC and NAC + BSO resulted in the lower level of proliferative capacity, higher level of necrotic lesions and higher apoptosis rate, respectively (Fig

Among these are glucosinolates (-thioglucoside N-hydroxysulfates), including glucoraphanin found in all members of the plant family Brassicaceae, which encompasses a large number of commonly consumed species in the Brassica genus [67], including the species Brassica oleracea better known as cruciferous vegetables such as broccoli, cauliflower, cabbage, kale, Brussels sprouts, kohlrabi, and collard greens [68]

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Problems and suggestions on the research status of quality standard of Mongolian medicine

Age-related macular degeneration (AMD), the most common cause of irreversible vision impairment in aged population in developed countries, is characterized by retinal pigment epithelium (RPE) damage, extracellular drusen, death of photoreceptors, and neovascularization (22)