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It is also worth noting that animal model studies have illustrated a mechanistic contribution of microbial TMA and TMAO generation to enhanced development of atherosclerosis, platelet reactivity and thrombosis, and both impairment in renal function and fibrosis, as well as adverse ventricular remodeling and heart failure (refs

These results indicated that in the in vitro phagocytosis model, the BsNb-ncAA exhibited improved capability to inhibit immune evasion and had stronger biological activity than the fusion protein PV2-PV3

The liver, which stores B12, can be compromised by excessive alcohol intake, leading to higher B12 requirements

Mushrooms and dairy products also contain high levels of L-carnitine