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Vitamin B5 (pantothenic acid): Pantothenic acid is involved with cellular energy metabolism and synthesizing the neurotransmitter acetylcholine, which is involved with muscle contraction, memory, motivation, and learning

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This slows down the transmission of electrical signals in the brain and peripheral nervous system, manifesting clinically as slowed processing speed, memory recall issues, and peripheral neuropathy (tingling or burning sensations in the hands and feet)

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2,7 This study demonstrates that these alkaloids have a high binding affinity for 5-HT 1A R and 5-HT 2B Rs (relative to mitragynine, the predominant alkaloid in kratom) but do not activate canonical G-protein mediated signal transduction through these receptors