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Downregulation of SIRT6 reversed the protective effect of caloric restriction mimetics during in vitro brain ischemia/reperfusion

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Damage to mitochondria resulting from iron overload leads to a reduction in ATP synthesis, which may impair cardiac contractility [66, 67]

Li Q, Yang Y, Wang H, et al

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To extract CF and CA, the separated skin layers were cut into small fragments and homogenized in 1 mL of ethanol to aid compound extraction [56, 57]