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3.3.2 Reduction of ECM degrading enzyme induction and inflammatory cascades Reactive aldehydes such as 4-HNE and MDA and other secondary products generated during lipid peroxidation are not merely markers of cellular damage but also potent biological signaling molecules

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GHK-Cu also stimulates collagen production in fibroblasts and promotes angiogenesis through VEGF upregulation, improving the blood supply and structural matrix that follicles depend on

T.KersemansV.MichotteY.et al (2005)